Guiseley spurned the chance to chalk the first win of Mark Bower’s tenure after gifting Histon an equaliser, with Shaquille McDonald coolly slotting home.
Loanee Louie Swain had a half chance early on but his shot lacked power and Ben Parker’s cross a found no takers before the two combined only to see Swain’s header turned round the post.
Michael Potts’ weaving run and shot under Calum Kitcha looked like the opener but Grant Roberts did well to get back and clear.
But the Lions’ pressure paid on 32 minutes as Alex Johnson got the better of Remy Clerima to rifle home.
He nearly doubled his tally shortly after with a curled effort just the wrong side of the post.
Wayne Brooksby’s shot-cum-cross nearly caught Kitscha out before Histon had their first meaningful shot on the hour.
The lively Swaine had a shot parried and Michael Potts’ follow up came back of the underside of the bar before sloppy defensive play at the other end left McDonald to round Steven Drench and equalise.
Histon grew in confidence after the goal but Brooksby wasted a golden opportunity to clinch it when he chose to cross instead of shoot and Craig Hobson headed just over the bar in the closing stages.
Mark Bower’s post-match interview
Entertainment value: ***
Man of the match – Jack Rea
Scorers: Guiseley –Johnson 32; Histon McDonald 73
Teams: Guiseley – Drench, Holdsworth, Meynell, Potts, Lockwood, Lawlor, Brooksby, Rea, Swain (Hobson 75), Johnson, Parker (Burns 68) Subs not used: Ible, Williams, Dickinson
Histon: Kitscha, Beckles (O’Malley 90), October, Roberts, Clerima, Grant, Taaffe, Clunan (Dowie 58), McDonald, Sheppard (Hicks 51), Day Subs not used: Hoban, Freeman
Referee: Glen Hart